Definition
Variola major refers to the most severe and common form of smallpox. 💀 It's caused by the Variola virus. This form of the disease is characterized by an extensive rash, high fever, and significant mortality. Before eradication, Variola major caused devastating epidemics. Think of it as the 'bad boy' of smallpox strains. It had a higher death rate than variola minor. Understanding its characteristics was crucial to eradication efforts.